Senior Scientist II, ADME

The role of Senior Scientist II, ADME within the Drug Disposition (DD) group at Novartis in Basel, Switzerland, involves supporting drug discovery and development through advanced in vitro ADME models. The company, Novartis, is dedicated to reimagining medicine and improving patient lives through innovative science and a collaborative approach. The main day-to-day responsibilities include performing and developing assays, analyzing complex datasets, and communicating study outcomes to multidisciplinary teams. The scientist will also contribute to scientific strategy, prepare technical reports, and ensure compliance with quality standards and project timelines. Additionally, the role involves driving the development of innovative cell-based DDI assays to enhance the in vitro assay portfolio. To qualify for this position, candidates must have an MSc or PhD in a relevant life science discipline. Essential requirements include extensive hands-on experience with mammalian cell culture and cell-based assays, as well as experience with advanced in vitro models like 3D cultures, organoids, or co-culture systems. A strong understanding of ADME sciences and drug-drug interactions, along with proficiency in bioanalytical techniques such as LC-MS/MS, is crucial. The role also demands the ability to develop, optimize, and troubleshoot complex in vitro assays, as well as strong data analysis, interpretation, and scientific communication skills. Nice-to-have skills include proficiency in Adobe Photoshop, Chemistry, and the use of an Oscilloscope. The role offers a collaborative work environment within a multidisciplinary team, with opportunities for professional growth and development. The location in Basel, Switzerland, provides a dynamic and inclusive work setting, with benefits such as flexible working options, parental leave, and a variety of competitive benefits in kind. What the role asks for: - MSc or PhD in a relevant life science discipline. - Extensive hands-on experience with mammalian cell culture and cell-based assays. - Experience with advanced in vitro models, including 3D cultures, organoids, or co-culture systems. - Strong understanding of ADME sciences and drug-drug interactions. - Experience with bioanalytical techniques, in particular LC-MS/MS. - Proven ability to develop, optimize, and troubleshoot complex in vitro assays. - Strong data analysis, interpretation, and scientific communication skills. - Demonstrated ability to work collaboratively in multidisciplinary project teams.